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CRISPR – Cas 9 Knockout

With CRISPR-Cas9 I have conducted a targeted knockout of a DNA-region encoding for a certain protein (working with leukocytes). My question is, how long does it take untill this protein is not detecable any more (e.g. via surface staining + flowcytometry) after the DNA has been manipulated? Or in other terms: how often are transcription, […]