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Retrosynthesis of spirocyclic compounds?

I have been trying to complete this retrosynthesis problem for a few days but can’t figure out how to get from Ester starting compound to a spirocyclic compound. I have tried removing the Ester but can’t figure out what best to replace it with. I have access to any reagents and starting materials as long […]

Categories
Ask Chemistry

Retrosynthesis of spirocyclic compounds?

I have been trying to complete this retrosynthesis problem for a few days but can’t figure out how to get from Ester starting compound to a spirocyclic compound. I have tried removing the Ester but can’t figure out what best to replace it with. I have access to any reagents and starting materials as long […]