CoV SARS killed or depleted with temperature & humidity conditions – Is there any such R&D for Corona Covid-19 virus?
The Effects of Temperature and Relative Humidity on the Viability of the SARS Coronavirus
We and others have reported that infectivity of SARS CoV (SARS coronavirus) was lost after heating at 56°C for 15 minutes but that it was stable for at least 2 days following drying on plastic. It was completely inactivated by common fixatives used in laboratory [9, 10]. Another study showed that it was inactivated by ultraviolet light, alkaline (), or acidic () conditions . Human coronaviruses have been shown to survive in PBS or culture medium with 5–10% FCS for several days [12–14] but they only survive a few hours after drying [13, 14]. There have been some studies reporting an association between the SARS outbreak, metrological factors, and air pollution [15–17]. Thus, information on the survival of the SARS coronavirus (SCoV) in the environment at different temperature and humidity conditions is of significant interest to understanding virus transmission.
First data on stability and resistance of SARS coronavirus compiled by members of WHO laboratory
The below table provides the first compilation of data on resistance of the SARS Coronavirus against environmental factors and disinfectants. This information has been provided by Members of the WHO multi-center collaborative network on SARS diagnosis. More detailed information on methods utilized and material used is being compiled and will be available shortly. The major conclusions from these studies are:
Virus survival in stool and urine
Virus is stable in faeces(and urine) at room temperature for at least 1-2 days.
Virus is more stable (up to 4 days) in stool from diarrhea patients (which has higher pH than normal stool).
Virus loses infectivity after exposure to different commonly used disinfectants and fixatives.
Virus survival in cell-culture supernatant
Only minimal reduction in virus concentration after 21 days at 4°C and -80°C.
Reduction in virus concentration by one log only at stable room temperature for 2 days. This would indicate that the virus is more stable than the known human coronaviruses under these conditions.
Heat at 56°C kills the SARS coronavirus at around 10000 units per 15 min (quick reduction).
Fixatives (for use in laboratories only)
SARS virus fixation (killing) on glass slides for immunofluorescence assays in room temperature does not kill virus efficiently unless the acetone is cooled down to -20oC.